Q: Does Find My iPhone work after a remote wipe and a lock of the SIM card?
A: Find My iPhone will not work after a Remote Wipe as at that point you’re effectively returning it to its original factory settings, erasing your Find My iPhone configuration along with everything else on the device.
On the other hand, the Remote Lock feature will not prevent you from locating your iPhone, as it simply sets a passcode on your device in much the same way as if you set one up manually from the Settings app. Note that this is not a SIM card lock—to lock or deactivate your SIM card you would need to contact your cellular carrier. Doing this would affect your ability to use the “Find My iPhone” feature as the iPhone would no longer have a cellular data connection, meaning you would only be able to locate it if the iPhone were connected to a Wi-Fi network.