iPhone Software 2.2.1 causing iTunes crashes

A large number of iPhone users are reporting on Apple’s discussion boards that iTunes crashes upon trying to sync after installation of Software 2.2.1. Interestingly, the crashes do not appear isolated to the iPhone, as some users have reported that iTunes will crash when trying to sync an iPod as well; others have said that the failed syncs have left them with corrupted audio files on the iPhone. Some users have suggested the problem lies with Apple’s DRM, as they have been able to successfully sync all non-DRM’d content. In addition, at least two iPhone users reported being able to sync after downloading application updates through iTunes, however, it is unknown whether this workaround will work for all affected users.